Nanoscale insights into chromatin integrity molecular rearrangements upon DNA damage response
DNA Double Strand Breaks (DSBs) threaten genomic stability, leading to cell death, chromosomal rearrangements, and cancer-driving mutations.
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Cryo-EM Structures of Infectious Low-Twist α-Synuclein Filaments in Lewy Bodies
-Synuclein (aSyn) aggregation within Lewy bodies underlies Parkinson's disease and associated dementias. These aggregates are often comprised of amyloid filaments, most of which appear untwisted or…
Mafb-lineage activation of a short polyalanine (+5) PHOX2B mutation produces severe respiratory dysfunction with preserved postnatal weight gain among survivors in a mouse model of congenital central hypoventilation syndrome
Rationale: Congenital central hypoventilation syndrome (CCHS) is most commonly caused by polyalanine repeat mutations in PHOX2B.
Synergistic inhibition of Notch signaling and forced cell cycle re-entry drive Müller glia reprogramming in uninjured mouse retina
In regenerative species, such as teleost fish, Müller glia (MG) autonomously re-enter the cell cycle after injury and give rise to functional retinal neurons.
Screening the MMV Pathogen Box reveals the mitochondrial <i>bc</i><sub>1</sub>-complex as a drug target in mature <i>Toxoplasma gondii</i> bradyzoites
The apicomplexan parasite Toxoplasma gondii infects 25–30% of the global human population and can cause life-threatening diseases in immunocompromised patients.
Ferrari’s first EV Luce targets GCC market as short commutes, younger drivers boost electric supercar appeal
Dubai: Ferrari believes the Middle East could prove particularly well suited to its first fully electric car, with shorter everyday journeys reducing one of the biggest concerns buyers typically…
He fought first for a MyKad, then for his people
Paulus Balan’s journey from a remote Sarawak village to becoming an advocate for his community spans education, identity and decades of determination.
Criticising governments is easy, taking over much harder
Balancing short-term political survival with long-term institutional reform requires extraordinary wisdom.
Dari tiada MyKad hingga diiktiraf Bumiputera, perjuangan panjang anak Sa’ban
Sa’ban antara 12 kaum ditambah dalam senarai peribumi Sarawak menerusi RUU Tafsiran (Pindaan) 2022 yang berkuat kuasa pada 1 Nov 2023.
Scientists test underwater solar panels that work 10 meters beneath the waves —breakthrough perovskite tech could support self-powered marine drones
Scientists have developed solar panels that can operate at depths of up to 10 meters underwater.
How, Exactly, Could A.I. Kill Us?
Employees of A.I. companies are increasingly sounding the alarm. What should we make of their warnings?
Apple’s India units go Pro as iPhone turns 18
- Apple's Indian factories produce iPhone 18 Pro and Pro Max models 24/7.
- Chartered flights transport new devices from India to global markets.
- Apple sells Pro and Pro Max models on launch day for the first time.
Aramco closes supply tap for Indian refiners
- Saudi Aramco halts crude supplies to Indian refiners
- Pipeline interruption affects 9% of India's crude imports
- Refiners face higher prices and freight costs due to conflict
EQT plans to invest $50 bn in India by 2030
- EQT plans to invest $50 billion in India by 2030.
- $2 billion annual investment, tripling capex from current levels.
- Joint venture with Adani Group for green data centers in major hubs.
Melaka polls to test PH’s strength, ties with BN, says analyst
THE coming Melaka state election will be a test not only of who controls the 28 seats in the state assembly, but also of how well Pakatan Harapan (PH) can manage its increasingly complicated…
- Melaka state election tests PH's resilience and BN relationship.
- PH must balance governing with maintaining identity, reform agenda.
- Election timing aligns with Umno's push to regain stronger mandate.
Oil extends slump as Saudi Arabia moves to restore key pipeline
It is the biggest drop in more than six weeks.
- Oil prices drop 3.2% to $102 a barrel, lowest since August 4
- Saudi Arabia aims to restore half East-West pipeline capacity within days
- Pipeline restoration expected in six weeks, crucial for Middle East oil flows
StanChart Sees Higher Oil Floor as Hormuz Crisis Spreads to Saudi Export Routes
Oil prices pulled back but remained elevated ahead of a critical Fed decision on Wednesday, with market expectations shifting towards a prolonged US-Iran conflict.
- Oil prices remain high despite Fed rate hike
- US-Iran tensions threaten Saudi export routes
- Houthi attacks heighten Red Sea transit risks
Critical Metals says it has ‘cracked’ eudialyte hurdle, plans $2.2B a year refinery in Romania
Preliminary refinery study outlines a joint venture designed to process feedstock from its Tanbreez rare earth project in Greenland.
- Critical Metals claims breakthrough in eudialyte processing technology
- $2.2 billion-a-year refinery planned in Romania for Tanbreez project
- Multistage mixed-acid leach process aims to reduce waste and generate revenue
Macklemore to donate Loop tour earnings to Gaza charities
US rapper Macklemore has donated his net earnings from Ed Sheeran's Loop Tour, one million US dollars (€872,000), to charities supporting Palestinian people.
Macklemore to donate $1m to Palestinian charities
US rapper Macklemore has donated his net earnings from Ed Sheeran's Loop Tour, one million US dollars (€872,000), to charities supporting Palestinian people.
Stephen A. Smith 'Very Concerned' About Lions Despite Week 1 Win
ESPN personality Stephen A. Smith raised serious issues for the Detroit Lions before their Week 2 game against the Buffalo Bills.
- Stephen A. Smith expresses concern about Detroit Lions despite Week 1 win.
- Lions defense allowed 469 yards and converted over half of third-down attempts.
- Smith believes Lions need Week 2 win to regain confidence.
Gold Holds Decline After Fed Tilts Hawkish and Raises Rates
Gold held a decline after the Federal Reserve raised interest rates for the first time in three years and signaled another hike was likely before year-end.
4 Mexican hotels from 4 different states among world’s ’50 Best Hotels’
It's no coincidence that the four Mexican hotels honored at the worldwide level are all beachside luxury resorts, taking full advantage of the natural wonders of the states of Yucatán, Quintana Roo…
Is Australia’s ‘voracious’ illicit drug use behind organised crime violence? It’s complicated
The escalation of organised crime violence could be due to a multitude of reasons – including illicit drug consumption.
- Illicit drug use in Australia has risen to 17.9% of the population.
- Ecstasy use dropped 74%, but amphetamine-related offences increased 14%.
- Methamphetamine consumption reached a ten-year high.
New laws on mining objections 'hacking at safety net'
Proposed laws in Queensland would restrict who can object to a mine and give politicians greater control over whether objections are heard in court.
New hope for breast cancer patients as life-extending drug now on NHS in England
Enhertu, which can give patients an extra seven months to live on average, has been prescribed in Scotland for more than two years and is available.
New transatlantic alliance?: Trump threatens EU over planned rapprochement with Canada
EU Commission President Ursula von der Leyen has caused a stir with a proposal. It's about Canada, the US neighbour. How will President Trump react to it?
Musk’s long-time backer is giving SpaceX stock to its investors
Valor Equity Partners is handing out stock to its LPs instead of cash returns.
- Antonio Gracias, board member of SpaceX, distributes SpaceX stock to investors.
- Gracias gives away 8.5% of Valor Equity Partners' SpaceX holdings, valued at $8.5 billion.
- Transfer aims to provide tax benefits and prevent market flooding.
BackOps Raises $42M to Scale AI Supply Chain Automation
BackOps Raises $42M Series B For AI Resolution BackOps has raised $42M in Series B funding to expand its AI resolution platform. Insight Partners led the round.
Tinashe Has One Rule Before Agreeing to Be an Opening Act: Here’s Why Harry Styles Made the Cut
The R&B singer explains why the Together, Together tour was an easy yes at the Spotify x Coach event in New York.
Florida woman pleads guilty to defrauding fund for Jeffrey Epstein victims
NEW YORK (AP) — A Florida woman who was paid $750,000 by a fund for people sexually abused by Jeffrey Epstein has pleaded guilty to falsifying records she used in her application for the money.
Prince Royce Speaks Out About Omission of Bachata in 2026 Latin Grammys Nominations: ‘It’s About Representation’
The artist noted that none of the nominees for best merengue/bachata album belong to that genre.
Coast Guard and FBI boarded tankers due to cyberattacks. How big is the risk?
U.S. Coast Guard personnel and FBI agents boarded two Texas-bound energy tankers last month after cyberattacks struck the vessels while they were traveling toward the United States, according to U.S. officials.
Anthropic brings Cowork directly inside Claude’s chat interface
Anthropic PBC said today it’s trying to make life simpler for its customers by merging its regular chatbot Claude with its agentic artificial intelligence tool Claude Cowork. The merger, which went into effect immediately, came as the company introduced two new features in beta.
Everything New in iOS 27.2 Beta 1
Apple surprised us with the first beta of iOS 27.2 today instead of releasing an iOS 27.1 beta. Apple likely went straight to iOS 27.2 to keep iPhone Duo code under wraps for now, since we already know the ‌iPhone Duo‌ will ship with iOS 27.1 when it comes out in October.
How Kenneth Branagh and Boyd Holbrook Approached Playing Real-Life People in ‘Atonement’
TIFF 2026: This harrowing drama is based on an actual incident from the Iraq War The post How Kenneth Branagh and Boyd Holbrook Approached Playing Real-Life People in ‘Atonement’ appeared first on…
OpenAI launches a new framework to track and investigate rogue AI agents
OpenAI released a framework for investigating and publicly reporting model misalignment, alongside six reports detailing concerning behavior.
Al Gore has a surprisingly calm take on the AI data center backlash
In an interview with TechCrunch, Al Gore suggested he isn't losing sleep over AI data center emissions — he's more worried about the AI industry's own warnings about where the technology is headed.
Meet Dyson's New Robot Vacuum Line: The Dyson Nurovi Line (2026)
The Nurovi line includes three lidar-powered robovacs. But to get the model I’m most intrigued by, you’ll need a Costco membership.
Snap tries to bring AR glasses to enterprise market, partnering with Nvidia, AWS and Salesforce
Snap is partnering with Nvidia, Amazon Web Services and Salesforce as part of an enterprise sales push centered on its $2,000 Specs AR glasses.
Device simulates natural conditions to grow biofilms and test their antibiotic susceptibility more accurately
Biofilms are complex microbial communities that adhere to a surface and encase themselves in a viscous matrix they produce.
Hot electrons reveal electronic collisions may raise resistance in twisted graphene
When a material heats up, its electrical resistance often rises. The harder question is what, exactly, is getting in the way. The electrons carrying the current may be scattered by vibrations of the material's atomic lattice, known as phonons. They may also collide with one another.
Save an Extra 10% Off the New SteelSeries Aeon Pro Wireless Gaming Controller With Infinite Battery Life
Quite possibly the best wireless PC and Xbox gaming controller ever.
Here’s What Snap’s Expensive Specs Can Actually Do
Snap thinks its chunky, pricey smart glasses are the future of human computing, powered by a new AI app and features that do everything from translating languages to improving your golf swing.
I wore the new Snap Specs — the design is wildly polarizing, but the instinctual computing is a genuine breakthrough
I tested the new standalone Snap Specs in Santa Monica. Divisive design and price aside, here is why its palm-based instinctual AR computing is a triumph.
Snapchat launches its own AI — and says Snap Intelligence will 'anticipate your needs'
Snap Intelligence is a new AI platform from Snap that promises to carry your personal context across devices.
I Tried Snap Specs: Really Big, but Also Like Nothing Else Out There
A business tool, or a theme park for my face? Right now I’m leaning toward the latter.
Cricket Wireless Adds 5G Home Internet Service
Cricket joins the club of mobile providers bundling home internet with mobile phone service.
Veridion Raises $20M to Expand AI-Powered Business Intelligence
Veridion Raises $20M Series A For Business Intelligence Veridion has raised $20M to expand its AI-powered business intelligence platform.
IndyCar Rookie Of The Year Dennis Hauger Gets A Big Break With AJ Foyt
Dennis Hauger won INDYCAR Rookie Of The Year in 2026 for Dale Coyne Racing. That earned him a multi-year contract at AJ Foyt Racing as Hauger takes over the No. 14 Chevy.
Bank of England to hold rates but energy shock stirs talk of a hike
British natural gas and Brent crude futures have leapt by nearly 20% this month
Abu Dhabi changes hotel classification standards with 7 new accolades
Abu Dhabi launches new hotel classification standards covering guest experience, sustainability and service quality, alongside seven new accolades
Building big with DNA gets a software upgrade
Forty-four years ago, Nadrian Seeman published his groundbreaking ideas on using DNA as a structural material, expanding DNA's significance far beyond its role as a carrier of genetic information.
The Italian dog breed helping farmers protect their livestock
Pest animals cost Australia's farmers about $1 billion a year, but maremma guardian dogs could play a vital role in protecting vulnerable livestock.
Climate Change: Analysis: Global Warming Increased Risk of Flash Floods in Nepal
The rapid warming in the Himalayas is exacerbating risk factors for flash floods like the one in Nepal in August. According to experts, these can continue to occur.
Genetic risk for PTSD may vary depending on the type of trauma experienced, large study suggests
A study reveals that your genes may make you more vulnerable to post-traumatic stress disorder (PTSD) from certain types of trauma—particularly childhood neglect—than from others.
Nearly a decade of research strengthens the case for vitamin D in pregnancy
A common and often overlooked nutrient deficiency may play a bigger role in pregnancy outcomes than previously recognized. In a recent analysis published in the Journal of Perinatology, neonatologist and pediatrician Carol L. Wagner, M.D., and Anjali G. Borsum, an M.D.
Crocodiles, Hippos, and Malaria Are Just Some of the Dangers in the Congo Basin
Learn how flooding, dangerous wildlife, and tropical diseases could complicate Ash Dykes’s 400-mile kayak trip through the Congo Basin.
30 Organizations, 7 Nations, 1 Problem: My Normative Enters Next Phase to Address the Trillion Dollar Global Women’s Health Equity Gap
CALGARY, Alberta — Modern Medicine has lacked a shared language to fully serve Women’s Health, until now. Canada based My Normative, a Women’s Health research and innovation platform currently serving 12 projects across 5 countries, launched The Persons Project (TPP) to advance the field of Women’s Health through improved data liquidity…
Early changes in the tumor environment may explain why immunotherapy works for some patients but not others
Two patients receive the same immunotherapy for the same cancer. In one, the tumor retreats and stays gone for years. In the other, the treatment does nothing. Oncologists still have no reliable way to tell these patients apart before therapy begins. Why does immunotherapy succeed for some and fail for others?