Barcelona team develops AI that detects ageing in blood stem cells
ChromAgeNet has decoded chromatin architecture, the 3D organisation of DNA in the nucleus, distinguishing young from aged blood stem cells and opening new paths for cell rejuvenation.
In a breakthrough for regenerative medicine, a team of scientists in Barcelona has created ChromAgeNet, an artificial intelligence tool that can detect ageing in blood stem cells. By analysing the three-dimensional structure of DNA, ChromAgeNet reveals the subtle structural variations that occur as cells age. This information can help researchers identify potential interventions to slow down the decline of blood stem cells and restore their function.
The research, published in Aging Cell, demonstrates the tool's potential for screening treatments that could rejuvenate blood tissue and strengthen the immune system.
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