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Health & Medicine

USC scientists discover how to create a never-ending supply of cancer-fighting cells

USC scientists have discovered a way to create a potentially renewable supply of genetically engineered immune cells that can attack cancer and strengthen the body's natural defenses.

  • USC scientists develop method to create endless supply of cancer-fighting cells
  • Focus on immature immune cells called granulocyte-monocyte progenitors (GMPs)
  • Engineered cells slow down growth of blood and solid tumors in mice

Science

Tiny molecular changes, big microparticle deformation

Materials that change their shape upon exposure to light are attracting growing interest in applications such as soft robotics, microscale actuators and smart materials. However, the connection between molecular-level structural changes and larger-scale deformation remains incompletely understood.

Health & Medicine

The FDA Must End Unnecessary Drug Trials | Opinion

The Food and Drug Administration should cut biosimilar trials to reduce costs, boost competition and improve patient access.

  • FDA drafts recommendations to streamline PK testing, potentially saving 50% costs.
  • Comparative efficacy studies may be redundant with other evidence establishing biosimilarity.
  • Regulators must adopt evidence-based guidelines excluding routine trials for biosimilars.
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