USC scientists discover how to create a never-ending supply of cancer-fighting cells
USC scientists have discovered a way to create a potentially renewable supply of genetically engineered immune cells that can attack cancer and strengthen the body's natural defenses. By growing and modifying immature immune cells rather than mature ones, researchers developed a system that can continuously produce tumor-fighting cells inside the body.
Scientists at the University of Southern California (USC) have discovered a method to generate a potentially endless supply of cancer-fighting immune cells. The team focused on immature immune cells known as granulocyte-monocyte progenitors (GMPs), which can develop into powerful immune fighters. By extending the lifespan of these cells in a lab setting, the researchers were able to create a scalable system for producing genetically engineered cells that target tumors and bolster the body's natural defenses.
These engineered cells were shown to integrate into mouse bone marrow, produce new immune cells, and slow down the growth of not only blood cancers but also solid tumors. The breakthrough could potentially revolutionize cancer treatment and open new avenues for treating various conditions.
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