Packers vs. Cowboys odds: Opening lines for Week 6 matchup
The two teams scored 80 points in last year’s meeting and are expected to have a high-scoring game again.
On Sunday, September 28, 2025, the Green Bay Packers faced off against the Chicago Bears in a resounding victory, winning 31-7 at AT&T Stadium in Arlington, Texas. Meanwhile, the Dallas Cowboys suffered a loss at home against the Tampa Bay Buccaneers, falling to 2-3 in the season. Despite the Cowboys' recent struggles, they are the favorites for their upcoming Week 6 matchup against the Packers at Lambeau Field, according to sportsbooks who opened on Sunday.
The opening line shows the Cowboys as 1.5-point favorites, according to FanDuel Sportsbook. Notably, the Packers were underdogs in both their Week 5 game against the Bears and their Week 5 game against the Bears, both of which ended up being blowout victories for the Packers. The last time the Packers were underdogs in back-to-back home games was in 2023, when they struggled to win both matches and ended up with a four-game losing streak that included road losses.
For their Week 6 game against the Cowboys, the sportsbooks are predicting a high-scoring affair, with the total points set at 52.5, which is the highest in any Week 6 game so far this season.
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