Cardinals vs. Rams odds: Opening lines for Week 6 matchup
Arizona Cardinals open as massive underdogs ahead of matchup with Rams.
In a surprising turn of events, the Arizona Cardinals, who entered the season as 1-4 underdogs, have opened as the biggest underdogs of the NFL season at +12.5 points ahead of their Week 6 matchup against the Los Angeles Rams. This is despite the Rams having yet to play their Week 5 game. The Cardinals' impressive victory over the Detroit Lions in their most recent game has fueled speculation about their potential to cover the spread.
However, for many Cardinals supporters, the question remains whether it's fair for the team to be perceived as two touchdown underdogs.
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