Proceedings of the National Academy of Sciences, Volume 123, Issue 35, September 2026. SignificanceEndogenous nucleic acids, including DNA and RNA, possess immunostimulatory features that, under normal cellular conditions, remain contained. Cellular stress, injury, or pathogenic infection releases endogenous nucleic acids to trigger innate ...
Twenty-nine reindeer introduced to St. Matthew Island in 1944 grew to over 6,000 animals. This population boom led to severe overgrazing of the island's lichen food sources.
