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Health & Medicine

Mechanical history shapes phenotypic plasticity and fibroblast-autonomous 3D remodeling in iPSC-derived cardiac fibroblasts

Human induced pluripotent stem cell-derived cardiac fibroblasts (iPSC-cFBs) offer a renewable, genetically defined stromal cell source for studying cardiac fibrosis and cardiomyocyte-fibroblast crosstalk during development and disease. Because cardiac fibroblasts are proliferative, expansion of iPSC-cFBs in culture is attractive for applications requiring large cell numbers, including drug…

We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.

Read the original at biorxiv.org →

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Did your toe / ankle / knee swell up out of nowhere and resolved in a few days? You may be having “GOUT ARTHRITIS”

When we think about arthritis, we usually imagine of diseases in which the joints gradually become swollen and painful over many years, eventually becoming deformed.

  • Gout is a sudden joint pain and swelling condition, often affecting big toe, ankle, knee.
  • Elevated uric acid levels cause gout, leading to crystal deposits in joints.
  • Untreated gout can cause joint damage, kidney complications if uric acid remains high.

DEALING WITH THE EBOLA THREAT

There should be effective mobilisation of trained health workers in addition to widespread public awareness campaigns on containment measures Early last May, the World Health Organisation (WHO)…

  • One confirmed Ebola case reported in Nigeria's FCT.
  • Patient arrived from Uganda via international flight.
  • Nigeria allocated N10 billion for emergency response.

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