Colts Lose Major Offensive Piece vs Titans

The Indianapolis Colts have lost a key offensive contributor as tight end Tyler Warren will miss the team's Week 6 game against the Tennessee Titans due to a worsening groin injury. The second-year player, acquired in the 2025 NFL Draft, was initially labeled with a questionable tag following a practice on Friday. According to NFL insider Adam Schefter, Warren's condition is worse than initially anticipated, leading to his inactivity for the upcoming matchup.

Warren, who holds the team's lead with 30 receptions and two touchdowns this season, was a standout pick, winning the John Mackey Award as the best tight end in 2024 during his time at Penn State. He made an immediate impact as a rookie with 76 catches for 817 yards and four touchdowns. Through the first five weeks of the current season, Warren has contributed 30 catches for 213 yards and two touchdowns.

The Colts will now need to rely even more on wide receivers Josh Downs, Keenan Allen, and Laquon Treadwell, along with backup tight end Mo Alie-Cox.