Early-onset spontaneous murine mammary tumors show increased lymphocyte representation and reduced MHC antigen presentation
Simple Summary Not all breast tumors behave the same way, and part of the reason may be inherited rather than caused by the tumor itself. Using mice that carry the same cancer-causing HER2/neu gene but differ in genetic background, we found that introduction of the PWK/PhJ genetic background was associated with tumors that appeared about a month earlier. These early tumors contained a larger…
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