PHC2-Dependent PRC1 Assemblies Stabilize Motor Neuron Hox Codes
Polycomb Repressive Complexes PRC1 and PRC2 establish and maintain chromatin architectures critical for cell-type specific gene expression. In the developing spinal cord, PRC1 is essential for implementing Hox-dependent transcriptional programs that diversify motor neuron identities. Although PRC1 can assemble into subnuclear condensates, whether these structures contribute to the specification…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
