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Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC

Nature Medicine, Published online: 13 September 2026; doi:10.1038/s41591-026-04488-2 In a large international real-world study of non-small cell lung cancer, a multimodal explainable AI model outperformed established biomarkers for immunotherapy outcome prediction and improved physician decision-making.

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