MxtR/ErdR is a central regulator of short-chain fatty acid metabolism in Pseudomonas alloputida

Short-chain fatty acids (SCFAs) such as acetate and propionate represent important carbon and energy sources for environmental pseudomonads, requiring coordinated regulation to ensure efficient assimilation while maintaining metabolic homeostasis. In Pseudomonas alloputida KT2440, the two-component system MxtR/ErdR (CrbS/CrbR) is known to activate acetate assimilation through regulation of…

biorxiv.org ·1d ago

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