A full-control strategy could cut simulated mpox infections by 97.8%, suggests mathematical model
Mpox (formerly monkeypox), a viral zoonotic disease, remains a global public health concern because it can spread between animals and humans and among people. While measures like vaccination, treatment, quarantine and public education are available, combining them strategically and allocating resources during an outbreak can be challenging.
A mathematical analysis published in Chaos, Solitons & Fractals suggests that a full-control strategy combining vaccination, treatment, quarantine and educational campaigns could reduce simulated mpox infections by 97.85%, making it the most cost-effective approach. Researchers from Hasanuddin University in Indonesia used a mathematical model to study the transmission dynamics between humans and rodents.
The model accounted for asymptomatic infections in humans and latent infections in rodents, revealing that rodent transmission could contribute to the disease's long-term persistence. The full-control strategy proved most effective, particularly during the early stages of an outbreak, while vaccination and treatment were maintained throughout the simulated outbreak.
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