Scientists may have found a shortcut to calorie restriction’s anti-aging benefits
Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments could mimic some benefits of calorie restriction without severe dieting.
Scientists may have discovered a potential shortcut to the anti-aging benefits of calorie restriction, according to a study published in Nature Aging. Researchers from Yale University found that reducing calorie intake by 14% over a two-year period led to a significant decrease in the levels of complement component 3 (C3), an immune protein.
This decrease in C3 is believed to be linked to a reduction in chronic inflammation, which is considered a major factor in aging and age-related diseases. The study, which involved 42 participants who followed a moderate calorie restriction diet without experiencing any detrimental effects on growth or reproduction, suggests that targeting the inflammatory response through C3 levels could be a viable approach for extending lifespan and promoting healthier aging in humans.
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