Evaluating Aggregated Gene Level eQTL Scores
Genetic feature engineering, used in methods such as transcriptome-wide association study, supports gene-trait association testing by aggregating single variants into gene-level features predictive of expression. To evaluate how different model architectures, LD filtering thresholds, and variant prioritization methods affect expression prediction quality, we trained over 3 million models and…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
