A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits

Non-coding regulatory variation drives complex traits, domestication, and evolutionary adaptation, yet the sheep genome lacks high-resolution functional annotation. Here we present SheepEpimap, a multi-tissue regulatory atlas harmonizing 516 CUT&Tag histone modifications, ATAC-seq, and RNA-seq datasets across 43 adult tissues in sheep. We annotated 2.93 million cis-regulatory elements, yielding…

biorxiv.org ·18h ago

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Intelligent people tend to perform better at school and at work, as numerous studies have shown. But what happens in domains where incentives such as good grades or financial rewards don't apply and where socioeconomic status is not a significant factor? Wine knowledge is a case in point.

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Musk's SpaceX to build $100bn launch site in Louisiana

The project - named Starbase - will be the firm's biggest facility yet and aims to send rockets to space in 2029.

18h ago ·bbc.co.uk

Musk's SpaceX to build $100bn launch site in Louisiana

The project - named Starbase - will be the firm's biggest facility yet and aims to send rockets to space in 2029.

18h ago ·bbc.co.uk

Strong oyster reefs start with genetic diversity

The European flat oyster (Ostrea edulis) was once widespread but has now become so scarce in the North Sea that it no longer forms ecologically functioning reefs. Along with the demise of the flat oyster, the three-dimensional structures that provide habitat for more than 100 marine species have disappeared.

18h ago ·phys.org