Multi-cohort analysis of 37,739 oral microbiomes reveals ecologically influential health-associated microbial sub-communities across major oral subsites

The oral cavity contains multiple microbial sub-niches, but which taxa consistently play an ecologically important, health-associated role within each niche, and how conserved they are across populations, remains poorly understood, partly due to the lack of a standardised identification framework. We developed a multi-cohort framework integrating 37,739 oral microbiome profiles (16S rRNA and…

biorxiv.org ·1d ago

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