Intracellular genomic variability driven by cellular compartmentalization in the giant bacterium Achromatium spp.

Bacteria of the genus Achromatium harbor hundreds of chromosomes that were previously suggested to be genetically diverse. By sequencing multiple regions from individual cells, we demonstrate that chromosomes within a single cell differ in nucleotide and amino acid sequence, reaching levels of divergence well below accepted bacterial species boundaries and below the range associated with…

biorxiv.org ·1d ago

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