HI-JEPA: A World Model of Molecular Organization Learned from Measured Proximity

Proteins act through the company they keep. Which molecules occupy the same nanoscale neighborhood in intact tissue determines what can physically interact, and disease rearranges those neighborhoods before it changes anything a sequence records. That quantity (measured proximity between molecular species in unperturbed tissue) has never been acquired broadly enough to train on. Published…

biorxiv.org ·12h ago

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