Fractionated ionising radiation affects cellular functions, and gene expression associated to subpopulation of F11 dorsal root ganglia neurons without inducing oxidative stress.

Radiotherapy is common practice to treat cancer but produces significant side effects such as chronic pain. Cancer survivors report developing chronic pain due to their treatment even long after the cancer is cured. To understand the mechanisms underlying the radiotherapy-induced chronic pain, we assessed how ionising X-ray radiation exposure during 4 consecutive days of 5 Gy (total radiation…

biorxiv.org ·21h ago

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