Breath-strip-like nanofiber film delivers three pain drugs in under two seconds
Children and seniors who have difficulty chewing and swallowing conventional tablets may have an easier way to find pain relief. Cornell researchers have developed an ultrafast-dissolving nanofiber film that can deliver a cocktail of three drugs so quickly and effectively that 90% of the formulation is released in less than two seconds.
Cornell researchers have created a nanofiber film that can rapidly dissolve and release three pain medications simultaneously. Led by associate professor Tamer Uyar, the team's electrospinning process produced a breath-strip-like film that releases 90% of acetylsalicylic acid, paracetamol, and caffeine in under two seconds. This is significantly faster than traditional tablets, which typically take much longer to dissolve.
The film's effectiveness stems from its cyclodextrin-based matrix, which enhances drug solubility and masks unpleasant tastes, making it easier for those with chewing difficulties to take. The nanofiber film's scalability and green manufacturing process through water-based electrospinning make it a promising alternative to conventional pain relief methods.
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