Cell-surface N-linked glycans manipulation of K562 cells for augmented susceptibility to natural killer cell killing
Glycosylation of proteins is arguably the most diverse post-translational modification that is altered in almost all cancer types, which has been demonstrated to play a crucial role in creating an immunosuppressive microenvironment that promotes immune tolerance and evasion. However, the biosynthesis of N-linked glycan is mediated by a series of enzymatic reactions catalysed by…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
