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Local fluidization of an active cytoplasmic gel partitions large cells

Early animal embryos undergo rapid cleavages that partition cytoplasmic volumes orders of magnitude larger than those of somatic cells. Each division must reposition nuclei and centrosomes and distribute organelles within minutes, over distances up to hundreds of micrometers. Cleavage furrows are positioned by microtubule asters, but the mechanical mechanism for long-range transport of…

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