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Palindrome in the sequence of the ribosomal peptidyl transferase center suggests a protoribosome emergence scheme

Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceUnderstanding how life emerged from nonliving matter is a central question in science. A key step in this transition would have been the spontaneous formation of a primitive ribosome, a “protoribosome,” capable of catalyzing peptide bond ...

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