New method maps DNA folding and epigenetic marks in single cells
A new experimental procedure developed by researchers at Yale School of Medicine could help scientists better understand how DNA structure influences disease and development.
Researchers at Yale School of Medicine have developed a new technique called Epi-PHR that can map both DNA structure and epigenetic marks in individual cells, potentially improving our understanding of how these factors contribute to disease and development. The method uses specialized molecules to bind to specific epigenetic marks or genes of interest, allowing researchers to observe how they interact and influence each other at the single-cell level.
This innovative approach could help identify specific genes involved in various conditions and potentially lead to the development of more targeted treatments.
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