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Deep learning-based gait analysis predicts multisystem health phenotypes

Nature Medicine, Published online: 09 November 2026; doi:10.1038/s41591-026-04725-8 We developed a gait foundation model from three-dimensional skeletal motion data of 3,328 deeply phenotyped adults, recorded using a depth camera during five motor tasks. Embeddings significantly predicted 1,887 of 3,210 phenotypic targets and provided predictive gains across all 18 body systems in men and 17 out…

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