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HIV-Blocking Antibody Shows Promise, but Resistant Strains Break Through

A new study finds that the VRC01 antibody initially protects against HIV infection, but resistant strains can cause breakthrough infections as antibody levels decline, highlighting the need for multiple antibodies.

  • Intravenous VRC01 antibody targets HIV-1 envelope glycoprotein
  • VRC01 provided 66.3% protection against sensitive strains
  • Resistant strains emerged post-treatment leading to breakthrough infections

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