Quantum Barcoding Bridges High-Dimensional Immune Phenotyping with Signaling Responses across Species

Cross-species immune profiling is limited by marker-panel size and antibody cross-reactivity. We benchmark Quantum Barcoding (QBC), a split-pool oligo-antibody assay, against mass cytometry in human and rhesus macaque blood and integrate separately measured cells using MARIO. The resulting computationally matched profiles carry 174 protein features. Population-frequency concordance was higher in…

biorxiv.org ·1d ago

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