Inflammatory Process Identified as Link Between Pulmonary Hypertension and Cognitive Decline
A study investigating the observed connection between pulmonary hypertension and cognitive decline symptoms has linked brain abnormalities in pulmonary hypertension to the same inflammatory processes that drive disease in the lungs and heart. The post Inflammatory Process Identified as Link Between Pulmonary Hypertension and Cognitive Decline appeared first on GEN - Genetic Engineering and…
A study by University of Pittsburgh and UPMC researchers has identified a link between pulmonary hypertension (PH) and cognitive decline. The team conducted a comprehensive investigation involving brain scans, blood tests, and mouse models, discovering specific brain abnormalities that connect pulmonary hypertension to inflammatory processes affecting the brain.
These findings suggest that cognitive decline may be a central part of the disease process in PH and could be present in other vascular and inflammatory conditions. Lead researcher Stephen Chan, MD, PhD, emphasized that patients should not dismiss memory issues or trouble concentrating as unrelated to their pulmonary hypertension.
The study, published in the Journal of Clinical Investigation, highlights potential neural targets for future diagnostic and therapeutic approaches, with implications for other inflammatory diseases that may contribute to dementia and aging.
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