Bone Response to Mechanical Loading is Highly Heritable and Correlates with Osteocyte Lacunar Morphology in Genetically Diverse Mouse Strains
Skeletal loading is a key regulator of bone formation. Studies using in vivo loading of rodent bones have established many mechanical and biological factors that regulate bone response to loading. However, most studies have been performed in a small number of inbred rodent strains, and there are few data on effects of genetic background on the loading response. In the current study we employed…
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