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Human Dengue Study Reveals How Preexisting Immunity Shapes Secondary Infections

A controlled human trial reveals how preexisting antibodies influence dengue virus replication and immune responses, offering insights to develop safer, more broadly protective vaccines against all…

  • Preexisting immunity impacts dengue severity.
  • Antibodies boosting viral replication cause higher viral counts.
  • Antibodies against NS1 protein lead to balanced immune responses.

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