Cisplatin Exposure Alters the Effects of Honokiol on Genes Involved in Outer Hair Cell Physiological Function
Outer hair cell (OHC) loss occurs in cisplatin-induced hearing loss (CIHL). We previously reported that honokiol protects against CIHL and mitigates cisplatin-induced transcriptomic changes in OHCs. Here, we re-analyzed OHC RNA-seq to determine whether honokiol differentially affects genes involved in OHC physiological function depending on cisplatin exposure. Twenty-two genes involved in…
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