Semaglutide Increases Striatal Leptin Sensitivity, Impacting Dopaminergic Response to Cocaine
There is accumulating evidence that the GLP-1 analog, semaglutide, might effectively curb intake of cocaine via brain dopaminergic functioning, despite limited brain penetrance. However, there is currently no established mechanism elucidating how chronic semaglutide treatment regulates the dopaminergic response to cocaine. Cocaine is a highly addictive substance that produces rewarding effects…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
