Cardinals vs. Rams: Key matchups to watch

The Arizona Cardinals will face off against the LA Rams in Week 6, with a few key absences impacting the matchup. Trent McDuffie, a crucial cornerback for the Rams, is currently out, leaving Jaylen Watson to face the Cardinals' only true wide receiver threat, Michael Wilson. On the Cardinals' defensive line, Josh Sweat and other outside linebackers will be tasked with taking on Dan Quessenberry, the Rams left tackle who is suspended for one game and has not started a game since 2023.

The Cardinals have faced minimal pressure from the edge thus far, but can they manage against a backup tackle like Quessenberry? Meanwhile, Rams tight end Garrett Williams will be in a familiar matchup against Cardinals cornerback Puka Nacua, who has amassed an impressive 17 catches on the season. Additionally, Cardinals offensive tackle Garrett Williams, who struggled in his first start at left tackle last week, will take on Rams defensive end Byron Young, who leads the Rams with 3.5 sacks.