Titans vs Colts picks as Tennessee tries to turn it around on the road

The Tennessee Titans enter Week 6 without a win, heading to Indianapolis to face the Colts in an AFC South divisional game on October 18. The Titans have struggled all season, going 0-5, with their worst outing last week against the Houston Texans, a 26-3 loss.

Indigenous (2-3) also suffered a tough home loss last week to the Pittsburgh Steelers in a difficult season that saw them face the Ravens, Chiefs, and Texans early on. Here's what the experts are projecting for the Titans-Colts matchup:

Titans' CEO Burke Nihill expresses remorse over the mounting losses.

Tyler Palmateer, a Titans beat reporter, believes Indianapolis' defense could give Tennessee a shot, but notes that Jonathan Taylor's running ability will be crucial. He concludes that this will likely be another underwhelming performance, with Cam Ward not getting enough chances to secure a win.

Columnist Gentry Estes leans towards Indianapolis at 31, Titans at 13, feeling that while Indianapolis isn't a strong team this season, he doesn't expect much from the Titans either.

Trending reporter Nick Gray suggests a closer game, with Indianapolis winning 27-17. He points to the Colts' defense as the best option for hope, but acknowledges Indianapolis' impressive streak of seven consecutive series wins.

Tom Kreager, Tennessean sports director, is skeptical of the Titans' offense, citing a significant setback against the Texans. However, he believes there's still potential for the Titans to score against Indianapolis. He does mention that the top pick in the 2027 NFL Draft remains in place, though.