2,234 attempts to harmonize a multi-platform B-cell lymphoma bulk transcriptomic dataset: ComBat is superior by cross-batch prediction quality
Background. Cross-platform transcriptomic harmonization benchmarks rely on individual success metric each: correlation with a reference profile, classifier accuracy, or a composite imported from single-cell integration. We found no published study that computes multiple orthogonal metric classes over one set of harmonization approaches and measures overlapping between the best approaches by these…
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