Sustained pressure halts cancer cell migration and triggers death in 3D lab models
The growth and death of cancer cells in the lab are studied primarily in two-dimensional cell cultures. In a study published in the journal Developmental Cell on Oct. 14, researchers instead used three-dimensional models to uncover how pressure and mechanical confinement impact cell growth—halting the cells' metastatic behavior and ultimately leading to their death. The findings could lead to the…
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