Intersectional genetic targeting of molecularly distinct melanin-concentrating hormone neuron subpopulations reveals distinct and overlapping subcircuit architecture
The lateral hypothalamic area (LHA) coordinates crucial and innate behaviors through heterogeneous yet poorly understood neuronal populations and circuits. Neurons that produce melanin-concentrating hormone (MCH; encoded by the Pmch gene) are primarily localized in the LHA and contribute to feeding, sleep-wake regulation, memory, and reward-associated behaviors. Building on foundational…
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