Projection-defined ventral tegmental area neurons exhibit distinct molecular adaptations during acute fentanyl withdrawal
Opioid use disorder (OUD) remains a major public health concern, with potent synthetic opioids driving overdose deaths. Understanding how synthetic opioids like fentanyl alter brain circuits to promote persistent use is critical for advancing OUD treatment. The ventral tegmental area (VTA), which projects to several other brain regions including prefrontal cortex (PFC), nucleus accumbens (NAc)…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
