Certified Design Regions under Parametric Plant Uncertainty with Application to Antithetic Integral Feedback
Kinetic parameters in engineered biomolecular circuits are typically known only within intervals and are not precisely tunable; controller synthesis is therefore naturally posed over sets of gains rather than at a single nominal design. We formulate robust controller tuning under parametric plant uncertainty as a universally quantified set-inversion problem: given a plant-parameter box, compute…
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