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The protective effect of NGF mutant CHF6467 in SH SY5Y cells exposed to Aβ(1-42): a pharmacometabolomic approach

Nerve Growth Factor (NGF) supports neuronal survival, plasticity, and growth by binding to p75NTR and TrkA receptors. There is a strong link between NGF and the cholinergic hippocampus, and changes in NGF pathways are observed in Alzheimer's disease (AD). Research shows NGF's neuroprotective and regenerative effects on cholinergic neurons, with positive results in AD models and clinical studies.…

We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.

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