Lipid Defect Analyzer (LipiDeA): A Python Framework for Quantifying Lipid Packing Defects in Curved and Neutral Lipid-Containing Membranes
Lipid packing defects expose hydrophobic regions of membranes and influence protein-membrane recognition, membrane remodeling, and lipid sensing. Quantitative analysis of these defects remains challenging for heterogeneous membranes with strong curvature, mixed bilayer and monolayer organization, and substantial neutral-lipid content. Here, we present Lipid Defect Analyzer (LipiDeA), an…
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