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Bone Marrow-Derived Cells Fuse with Bergmann Glia in Experimental Autoimmune Encephalomyelitis

Bone marrow-derived cells (BMDCs) can infiltrate the brain and adopt new identities through transdifferentiation or fusion, yet their interactions with specific neural cells remain poorly defined. We examined BMDC fusion with Bergmann glia (BG), a key cerebellar support cell, in a mouse model of multiple sclerosis. After bone marrow transplantation, BMDCs fused with BG to form heterokaryons,…

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