Candy-coated Lollylab checks saliva for medication
What if checking medication levels were as simple as enjoying a lollipop? A candy-coated device called Lollylab could provide the answer. In ACS Sensors, researchers describe how the lollipop's stem transfers saliva to a sensor that measures acetaminophen levels.
Imagine a lollipop that could detect medication levels in your saliva, all in under two minutes. Researchers have developed a device called Lollylab, a candy-coated tool designed to measure acetaminophen levels in saliva. The device comprises two plastic pieces, each with a round end and a thin stem, which are connected and have holes at the top for saliva to pass through.
A red, peach-flavored candy shell lines the top, with a glass fiber paper-lined stem leading to a graphene sensor at the bottom. This sensor measures acetaminophen levels as changes in electrical current.
In a trial involving six adults, the Lollylab prototype was able to detect acetaminophen in both artificial and human saliva samples. Participants were given a standard adult dose of acetaminophen, and the device reliably measured the drug in their saliva within less than two minutes. The researchers found that the Lollylab was more comfortable and easier to use than traditional saliva swabs, which could make it particularly appealing for children.
Acetaminophen, a common ingredient in over-the-counter pain relievers and cold medications, can cause serious side effects when taken in excess, including liver damage. Children are at higher risk of unintentional overdose due to lower dosage levels. Saliva levels of acetaminophen closely mirror blood levels, making it an attractive option for noninvasive monitoring.
The Lollylab is built to collect saliva samples and perform measurements on-site, eliminating the need for separate analysis. While the prototype showed promising results, further trials involving larger groups, including children, are necessary to validate its accuracy and effectiveness. Ultimately, the researchers aim to create a multi-assay platform capable of measuring various biomarkers in saliva, potentially leading to a comprehensive diagnostic tool.
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