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MIRTO: a registration-gated, multiverse-tested evaluation protocol for unsupervised anomaly segmentation in brain MRI

Unsupervised anomaly detection (UAD) methods for brain MRI are ranked by a single score, yet that score rests on choices that are rarely reported: how each anomaly map is aligned with the reference, how and on which data the threshold is set, and which false-positive budget, metric, aggregation and lesion definition are used. We present MIRTO, an evaluation protocol that makes these choices…

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