Combined lactate and hypothermia therapy enhances neuroprotection following neonatal hypoxic-ischemic brain injury
Background and Purpose: Neonatal hypoxia-ischemia (NHI) is a leading cause of mortality and long-term neurodevelopmental disability. Therapeutic hypothermia (TH) is currently the only established treatment for NHI; however, its efficacy remains limited, underscoring the need for adjunctive neuroprotective strategies. Lactate is now regarded as a major metabolic substrate of the brain and has…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
