The strength of a gene's first 5' splice site is a key determinant of its expression
The control of gene expression is central to cellular physiology and to various biotechnological applications. In higher eukaryotes, synthesis of most messenger RNAs involves removal of introns during splicing. Intron-containing genes are often more highly expressed than intronless versions, despite generating the same mRNA transcripts, suggesting that the splicing of transcripts from a gene…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
