Exercise as medicine—how exercise protects joints in aging-related osteoarthritis
Researchers at Mass General Brigham have found that moderate-intensity exercise alters circulating extracellular vesicles in ways that promote cartilage health and tissue resilience, identifying microRNA-29 as a key mediator that improved characteristics of aged cartilage cells and reduced signs of joint degeneration.
Researchers at Mass General Brigham have discovered that engaging in moderate-intensity exercise alters circulating extracellular vesicles, which in turn promotes cartilage health and tissue resilience, offering fresh insight into how physical activity protects joints from aging-related osteoarthritis. Published in Nature Aging, the study led by Drs. Hirotaka Iijima and Fabrisia Ambrosio identifies microRNA-29 as a key mediator of these benefits.
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