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Early complications common in older kidney transplant recipients

Early complications are common in older kidney transplant recipients, according to a study published in the October issue of Transplantation Direct.

Early complications common in older kidney transplant recipients

Older kidney transplant recipients are particularly susceptible to early complications, according to a study published in the October issue of Transplantation Direct. Researchers from Alma Mater Studiorum-University of Bologna in Italy examined 93 transplant recipients aged 65 and above, finding that 65.6% of them experienced a complicated in-hospital course.

Factors like longer dialysis history and donor hypertension were linked to an increased likelihood of complications such as hospital stays longer than 15 days, infection, delayed graft function, primary nonfunction, or in-hospital death. In contrast, preemptive transplantation and living donation were associated with a lower risk of these outcomes.

Over a median follow-up period of 29.8 months, patients with a complicated early posttransplant course had higher rates of adverse events, although these differences were not statistically significant in Cox regression analyses. Despite the higher short-term complications, the overall clinical outcomes and graft function were comparable between those with and without early complications, indicating that prompt identification and management of early complications could help prevent their long-term effects.

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